Computer-Aided Detection (CAD) technology involves the use of computers to identify suspicious areas on a mammogram after the radiologist's initial review of the mammogram. CAD double-checks the work of the radiologist. In 1998, the FDA approved the first CAD system. This device can either scan a mammographic film with a laser beam and convert it into a digital image, or obtain images directly from a digital mammography system. The radiologist can see if any of the highlighted areas require further evaluation.

Studies show that CAD, along with human review, can result in earlier detection of more cancers by 23.4%. Used in conjunction with film-based mammograms, CAD digitizes the image much like a photo that is scanned into a computer.

CAD technology makes evaluations more accurate by highlighting suspicious areas on a mammogram.